Mick McCarthy will use all his insider knowledge to defeat a side that have won once in six at home.
Ipswich are searching for a first goal in four Championship matches against the black-country club.
Wanderers have ended the calendar year on a winning note once in eight seasons, when defeating Liverpool 1-0 at Anfield in 2010.
If Ipswich are to progress up the table then taking points for their nearest rivals will be key.
So they will be looking for a fourth away victory against a bottom-half club, having already taken maximum points from Bolton, Birmingham and Charlton and gained a point at Barnsley.
Wolves Team News:
Winger Bjorn Sigurdarson may be given a starting place after impressing in the win as might defender Richard Stearman who is a transfer target for Town.
Wolves manager Stale Solbakken is expected to make changes to his side after their 3-0 home defeat against Peterborough on Boxing Day.
Player to watch: Ebanks-Blake
The striker will want to impress prospective new employers
Ipswich Town Team News:
Despite the risk of fatigue for some, Ipswich manager Mick McCarthy may keep faith with an unchanged side for a fifth successive match.
Player to watch: DJ Campbell
He scores at will
Match Facts & Stats
Ipswich to win 1-0
Home to Brighton on January 1